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Category Archives: helminth immunology

Who needs Humira when you can have worm shots?

Worm proteins injected intraperitoneally (shot in the abdomen) ameliorate colitis in mice. http://www3.interscience.wiley.com/journal/121530207/abstract?CRETRY=1&SRETRY=0 “Conclusions: Treatment with proteins of S. mansoni and A. caninum ameliorated TNBS-induced colitis in mice. S. mansoni proteins increased mRNA expression of regulatory cytokines while suppressing expression of proinflammatory cytokines. Therefore, we suggest a therapeutic potential for helminth proteins in the treatment [...]

MAP, Crohn’s, and helminths

One of the things those with Crohn’s disease ponder is the relationship between MAP (mycobacteria subspecies avian paratuberculosis) and helminths. MAP is one of the infections that some people think causes or contributes to Crohn’s, as it is abundant in our milk supply, survives pasturization and is very similar to Johne’s disease, which is basically [...]

Week 10: More worms?

Always an American, too many choices. Oh, the selection in the hookworm market! I can a) wait and get no more larvae; if I’m not better by X amount of months I can b) get more slowly – 2 or 3 every few weeks or c) get more quickly and possibly suffer the ill effects. [...]