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Category Archives: trials

Nottingham Hookworm Results for Allergies and Asthma

Disappointing. 10 hookworms didn’t really work statistically for asthma or allergies, but there were immune changes.  I wonder what “mimic most closely natural infection” means (last line of abstract for asthma study)? Less at once, more often? Or more than 10? I am feeing extraordinarily lucky that 10 hookworms caused such a pronounced change [...]

To the Medical Community, or Dear Dr. Weinstock

Article after article extolling the virtues of helminths’ ability to prevent allergies and autoimmune diseases always end in quotes like this:
“The hope is that the work could aid the development of new treatments which work in the same way as gut parasites, by dampening down or rebalancing the immune system so that the body does [...]

eosinophilia: significance?

There are very few studies on the effect of helminths on humans. As a patient trying this therapy, there are few immune markers we have on hand to check immune response. We have measures of inflammation, like CRP and SED rates, but only in the research setting can one measure IL-10, [...]

Nottingham’s Trial Notes

Just found the on-line protocol for the Crohn’s study at Nottingham University. For those of you with Crohn’s experimenting with hookworms, though most of the immune blood tests will be unavailable to us, it might be nice to follow some of the other protocol. The CRP and SED rate are taken at baseline, [...]

Week 4: Nottingham Trials

I just got an email from Nottingham. Inviting me to be in their Crohn’s disease trial, though they realized that distance could be a problem. The English was so proper:
“Whilst we would be delighted to have you participate in our trial, the tyranny of distance seperates us.” I don’t think I’ve ever used [...]