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	<title>Waiting for the Cure &#187; Cooke</title>
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	<description>... a day in the life of Crohn's disease ...</description>
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		<title>More articles on Hygiene Hypothesis</title>
		<link>http://waitingforthecure.com/I/2009/01/31/more-articles-on-hygiene-hypothesis/</link>
		<comments>http://waitingforthecure.com/I/2009/01/31/more-articles-on-hygiene-hypothesis/#comments</comments>
		<pubDate>Sat, 31 Jan 2009 13:29:03 +0000</pubDate>
		<dc:creator>I</dc:creator>
				<category><![CDATA[helminth immunology]]></category>
		<category><![CDATA[hygiene hypothesis]]></category>
		<category><![CDATA[news]]></category>
		<category><![CDATA[old friends' hypothesis]]></category>
		<category><![CDATA[Cooke]]></category>
		<category><![CDATA[Rook]]></category>

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		<description><![CDATA[Another article on worms and the hygiene hypothesis from the BBC. And a detailed, follow-up article that lists the three new Immunology articles that provoked these articles. The popularity of this in recent press is very exciting. Of course, they always say they&#8217;re looking for the molecule that the worms ilicit in order to treat [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://news.bbc.co.uk/2/hi/health/7856095.stm">Another article</a> on worms and the hygiene hypothesis from the BBC.  And a <a href="http://www.nhs.uk/news/2009/01January/Pages/WormsImmuneSystem.aspx">detailed, follow-up article</a> that lists the three new Immunology articles that provoked these articles.  The popularity of this in recent press is very exciting.  Of course, they always say they&#8217;re looking for the molecule that the worms ilicit in order to treat autoimmune diseases:</p>
<p>Professor Anne Cooke: &#8220;It will allow you to identify pathways of disease and allow you to modify them with small molecules, not the whole worm.&#8221;</p>
<p>&#8220;Before I would even consider treating a child with type 1 diabetes I would have to be sure it was safe and understand the mechanisms underlying it.</p>
<p>&#8220;We are talking about using fractions not the whole parasite.&#8221;</p>
<p>What they don&#8217;t recognize is that in the meantime, there are desperate patients like me, absolutely willing to try worms to alleviate our diseases.  Especially as the choices we have are so dangerous &#8211; a small colony of hookworms or whipworms that only cause transient side effects (and this is written by the side effect queen), or Tysrabi, with a 1 in 1000 chance of <a href="http://ms.about.com/od/glossary/g/pml.htm">progressive multifocal leukoencephalopathy</a>?  If I were a parent of a child with type 1 Diabetes, or Crohn&#8217;s, I would absolutely jump at the chance of trying a light hookworm infection rather than the alternative.  How many decades until Professor Cooke and others figure out those fractions of parasites?  I would lose another piece of my intestines.</p>
<p>We want worms now.</p>
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