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	<title>Waiting for the Cure &#187; helminth proteins</title>
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	<link>http://waitingforthecure.com/I</link>
	<description>... a day in the life of Crohn's disease ...</description>
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		<title>Who needs Humira when you can have worm shots?</title>
		<link>http://waitingforthecure.com/I/2008/12/10/who-needs-humira-when-you-can-have-worm-shots/</link>
		<comments>http://waitingforthecure.com/I/2008/12/10/who-needs-humira-when-you-can-have-worm-shots/#comments</comments>
		<pubDate>Wed, 10 Dec 2008 14:07:38 +0000</pubDate>
		<dc:creator>I</dc:creator>
				<category><![CDATA[helminth immunology]]></category>
		<category><![CDATA[studies]]></category>
		<category><![CDATA[helminth proteins]]></category>
		<category><![CDATA[helminth therapy]]></category>

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		<description><![CDATA[Worm proteins injected intraperitoneally (shot in the abdomen) ameliorate colitis in mice. http://www3.interscience.wiley.com/journal/121530207/abstract?CRETRY=1&#038;SRETRY=0 &#8220;Conclusions: Treatment with proteins of S. mansoni and A. caninum ameliorated TNBS-induced colitis in mice. S. mansoni proteins increased mRNA expression of regulatory cytokines while suppressing expression of proinflammatory cytokines. Therefore, we suggest a therapeutic potential for helminth proteins in the treatment [...]]]></description>
			<content:encoded><![CDATA[<p>Worm proteins injected intraperitoneally (shot in the abdomen) ameliorate colitis in mice.<br />
<a href="http://www3.interscience.wiley.com/journal/121530207/abstract?CRETRY=1&amp;SRETRY=0"></p>
<p>http://www3.interscience.wiley.com/journal/121530207/abstract?CRETRY=1&#038;SRETRY=0</a></p>
<p>&#8220;Conclusions: Treatment with proteins of S. mansoni and A. caninum ameliorated TNBS-induced colitis in mice. S. mansoni proteins increased mRNA expression of regulatory cytokines while suppressing expression of proinflammatory cytokines. Therefore, we suggest a therapeutic potential for helminth proteins in the treatment of IBD.&#8221;</p>
<p>This is probably the way helminth therapy will go.  A shot every 2 weeks in the abdomen.  No icky worms to think about.  All sterile and in a nice box in the fridge. No worries about worm death&#8230;I wonder if it will hurt as much as Humira&#8230;</p>
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