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	<title>Waiting for the Cure &#187; TSO</title>
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	<description>... a day in the life of Crohn's disease ...</description>
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		<title>TSO:  Why Not Get a Pig?</title>
		<link>http://waitingforthecure.com/I/2009/06/02/tso-why-not-get-a-pig/</link>
		<comments>http://waitingforthecure.com/I/2009/06/02/tso-why-not-get-a-pig/#comments</comments>
		<pubDate>Tue, 02 Jun 2009 14:04:55 +0000</pubDate>
		<dc:creator>I</dc:creator>
				<category><![CDATA[whipworm]]></category>
		<category><![CDATA[TSO]]></category>

		<guid isPermaLink="false">http://waitingforthecure.com/I/?p=627</guid>
		<description><![CDATA[For TSO users, because of the horrible expense, I&#8217;ve thought of a potentially elegant solution.Â  Why not get and infect a pig?Â  In most city ordinances, pot-belly pigs are allowed, and were quite popular in the 80&#8242;s as pets.Â  I&#8217;m told they are intelligent, trainable animals that can live with dogs happily.Â  I used to [...]]]></description>
			<content:encoded><![CDATA[<p>For TSO users, because of the horrible expense, I&#8217;ve thought of a potentially elegant solution.Â  Why not get and infect a pig?Â  In most city ordinances, pot-belly pigs are allowed, and were quite popular in the 80&#8242;s as pets.Â  I&#8217;m told they are intelligent, trainable animals that can live with dogs happily.Â  I used to live across the street from one, and it could be quite loud at times, but also was rather cute.</p>
<p>If one were to feed them a vial of trichuris suis, I imagine they would implant in the pig.Â  I don&#8217;t know the longevity of the pig whipworm, or the methods one would have to take in order to isolate the ova from the pig&#8217;s feces in order to avoid contamination and ingesting any fecal flora that one wouldn&#8217;t desire, but with a little research, I imagine it would be possible.Â  The pig whipworm was chosen since pig farmers have been exposed to this organism for a long time and were considered asymptomatic.Â  It could also be protective to people&#8217;s children, as contact with farm animalsÂ  is associated with a decrease in pediatric crohn&#8217;s disease.</p>
<p><a href="http://pediatrics.aappublications.org/cgi/content/full/120/2/354#F1">http://pediatrics.aappublications.org/cgi/content/full/120/2/354#F1</a></p>
<p>I wonder if using cow or horse manure on vegetable crops would be protective?</p>
<p>If anyone experiments with this idea; gets a pig and isolates the pig whipworm, please share with us your methods.</p>
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		<title>Asphelia Pharmaceuticals: the new TSO</title>
		<link>http://waitingforthecure.com/I/2008/12/01/asphelia-pharmaceuticals-the-new-tso/</link>
		<comments>http://waitingforthecure.com/I/2008/12/01/asphelia-pharmaceuticals-the-new-tso/#comments</comments>
		<pubDate>Mon, 01 Dec 2008 16:21:08 +0000</pubDate>
		<dc:creator>I</dc:creator>
				<category><![CDATA[helminth therapy]]></category>
		<category><![CDATA[whipworm]]></category>
		<category><![CDATA[pig whipworm]]></category>
		<category><![CDATA[trichuris suis]]></category>
		<category><![CDATA[TSO]]></category>

		<guid isPermaLink="false">http://waitingforthecure.com/I/?p=233</guid>
		<description><![CDATA[So it looks like TSO has been bought by Asphelia Pharmaceuticals, who supposedly has rights to all uses of TSO except for IBD in Europe. Here&#8217;s a link to their site: http://www.aspheliapharma.com/ And they have a fabulous video on the use of helminths for inflammatory diseases: http://www.aspheliapharma.com/media.html In their pipeline, they claim that they were [...]]]></description>
			<content:encoded><![CDATA[<p>So it looks like TSO has been bought by Asphelia Pharmaceuticals, who supposedly has rights to all uses of TSO except for IBD in Europe.    Here&#8217;s a link to their site:</p>
<p><a href="http://www.aspheliapharma.com/">http://www.aspheliapharma.com/</a></p>
<p>And  they have a fabulous video on the use of helminths for inflammatory diseases:</p>
<p><a href="http://www.aspheliapharma.com/media.html">http://www.aspheliapharma.com/media.html</a></p>
<p>In their pipeline, they claim that they were starting a trial for Crohn&#8217;s disease this Fall, but I contacted the CEO and he said due to funding issues, it&#8217;s been postponed, and to look for an announcement on clinicaltrials.gov for when the trial begins.  So for those with Crohn&#8217;s waiting for some free TSO, it may be a while&#8230;</p>
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